Feasibility of outpatient fully integrated closed-loop control: first studies of wearable artificial pancreas.

ABSTRACT:

Objective

To evaluate the feasibility of a wearable artificial pancreas system, the Diabetes Assistant (DiAs), which uses a smart phone as a closed-loop control platform.

Research design and methods

Twenty patients with type 1 diabetes were enrolled at the Universities of Padova, Montpellier, and Virginia and at Sansum Diabetes Research Institute. Each trial continued for 42 h. The United States studies were conducted entirely in outpatient setting (e.g., hotel or guest house); studies in Italy and France were hybrid hospital-hotel admissions. A continuous glucose monitoring/pump system (Dexcom Seven Plus/Omnipod) was placed on the subject and was connected to DiAs. The patient operated the system via the DiAs user interface in open-loop mode (first 14 h of study), switching

SUBMITTER: Kovatchev BP 

PROVIDER: S-EPMC3687268 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature