"Induced sputum versus gastric lavage for the diagnosis of pulmonary tuberculosis in children".

ABSTRACT:

Background

Diagnosis of pulmonary tuberculosis (PTB) is difficult in infants and young children. For microbiological confirmation of PTB children, sequential gastric lavage (GL) is recommended. Induced sputum (IS) may be an alternative or complementary tool, but the information is limited in children in developed countries. The aim of this study is to assess the safety and diagnostic yield from IS combined with GL for PTB diagnosis in non-HIV infected children.

Methods

The study involved 22 children with suspected PTB admitted to the Getafe Hospital from January 2007 to May 2011. IS and GL were performed on three consecutive days, according to a standardized protocol. In all samples, BK staining, culture and PCR were carried out, including Genotype MTBDR plus for resistance

SUBMITTER: Ruiz Jimenez M 

PROVIDER: S-EPMC3688294 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature