Overlapping genes of Aedes aegypti: evolutionary implications from comparison with orthologs of Anopheles gambiae and other insects.

ABSTRACT:

Background

Although gene overlapping is a common feature of prokaryote and mitochondria genomes, such genes have also been identified in many eukaryotes. The overlapping genes in eukaryotes are extensively rearranged even between closely related species. In this study, we investigated retention and rearrangement of positionally overlapping genes between the mosquitoes Aedes aegypti (dengue virus vector) and Anopheles gambiae (malaria vector). The overlapping gene pairs of A. aegypti were further compared with orthologs of other selected insects to conduct several hypothesis driven investigations relating to the evolution and rearrangement of overlapping genes.

Results

The results show that as much as ~10% of the predicted genes of A. aegypti and A. gambiae are localized in p

SUBMITTER: Behura SK 

PROVIDER: S-EPMC3689595 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature