Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis.

ABSTRACT:

Objectives

To summarise evidence on the associations of maternal anaemia and prenatal iron use with maternal haematological and adverse pregnancy outcomes; and to evaluate potential exposure-response relations of dose of iron, duration of use, and haemoglobin concentration in prenatal period with pregnancy outcomes.

Design

Systematic review and meta-analysis

Data sources

Searches of PubMed and Embase for studies published up to May 2012 and references of review articles.

Study selection criteria

Randomised trials of prenatal iron use and prospective cohort studies of prenatal anaemia; cross sectional and case-control studies were excluded.

Results

48 randomised trials (17 793 women) and 44 cohort studies (1 851 682 women) were included. Iron use increase

SUBMITTER: Haider BA 

PROVIDER: S-EPMC3689887 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature