Ultrafiltration in decompensated heart failure with cardiorenal syndrome.

ABSTRACT:

Background

Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute decompensated heart failure complicated by persistent congestion and worsened renal function.

Methods

We randomly assigned a total of 188 patients with acute decompensated heart failure, worsened renal function, and persistent congestion to a strategy of stepped pharmacologic therapy (94 patients) or ultrafiltration (94 patients). The primary end point was the bivariate change from baseline in the serum creatinine level and body weight, as assessed 96 hours after random assignment. Patients were followed for 60 days.

Results

Ultrafiltration

SUBMITTER: Bart BA 

PROVIDER: S-EPMC3690472 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature