Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme.

ABSTRACT: Peptidoglycan hydrolases are an effective new source of antimicrobials. A chimeric fusion protein of the Ply187 endopeptidase domain and LysK SH3b cell wall-binding domain is a potent agent against Staphylococcus aureus in four functional assays.

SUBMITTER: Mao J 

PROVIDER: S-EPMC3690576 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature