High-throughput sequencing of cytosine methylation in plant DNA.

ABSTRACT: : Cytosine methylation is a significant and widespread regulatory factor in plant systems. Methods for the high-throughput sequencing of methylation have allowed a greatly improved characterisation of the methylome. Here we discuss currently available methods for generation and analysis of high-throughput sequencing of methylation data. We also discuss the results previously acquired through sequencing plant methylomes, and highlight remaining challenges in this field.

SUBMITTER: Hardcastle TJ 

PROVIDER: S-EPMC3691832 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature