Effect of physical training on airway inflammation in animal models of asthma: a systematic review.

ABSTRACT:

Background

There is little data on the effect of exercise on markers of airway inflammation in human asthmatics. The main objective of this review is to determine the effects of physical training on markers of airway inflammation in animal models of asthma.

Methods

A peer reviewed search was applied to Medline, Embase, Web of Science, Cochrane, and DARE databases. Data extraction was performed in a blinded fashion.

Results

From the initial 2336 studies, a total of 10 studies were selected for the final analysis. All were randomized controlled trials with low to moderate intensity training on ovalbumin-sensitized mice. In the exercised group of mice, there was a reduction in BAL eosinophils and Th-2 cytokines, no change in Th-1 cytokines, an increase in IL-10, and a re

SUBMITTER: Luks V 

PROVIDER: S-EPMC3691924 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature