Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction.

ABSTRACT: One goal of the CASP community wide experiment on the critical assessment of techniques for protein structure prediction is to identify the current state of the art in protein structure prediction and modeling. A fundamental principle of CASP is blind prediction on a set of relevant protein targets, that is, the participating computational methods are tested on a common set of experimental target proteins, for which the experimental structures are not known at the time of modeling. Therefore, the CASP experiment would not have been possible without broad support of the experimental protein structural biology community. In this article, several experimental groups discuss the structures of the proteins which they provided as prediction targets for CASP9, highlighting structural and function

SUBMITTER: Kryshtafovych A 

PROVIDER: S-EPMC3692002 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature