Cognitive enhancement therapy for early-course schizophrenia: effects of a two-year randomized controlled trial.

ABSTRACT:

Objective

The early application of cognitive rehabilitation may afford long-term functional benefits to patients with schizophrenia. This study examined the two-year effects of an integrated neurocognitive and social-cognitive rehabilitation program, cognitive enhancement therapy (CET), on cognitive and functional outcomes in early-course schizophrenia.

Methods

Early-course outpatients (mean+/-SD illness duration=3.19+/-2.24 years) with schizophrenia or schizoaffective disorder were randomly assigned to CET (N=31) or enriched supportive therapy (EST) (N=27), an illness management intervention utilizing psychoeducation and applied coping strategies, and treated for two years. Multivariate composite indexes of cognitive, social adjustment, and symptom domains were derived from

SUBMITTER: Eack SM 

PROVIDER: S-EPMC3693549 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature