Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology--a systematic review.

ABSTRACT:

Background

Histopathology has initially been and is still used to diagnose infectious, degenerative or neoplastic diseases in humans or animals. In addition to qualitative diagnoses semiquantitative scoring of a lesion`s magnitude on an ordinal scale is a commonly demanded task for histopathologists. Multiparametric, semiquantitative scoring systems for mouse models histopathology are a common approach to handle these questions and to include histopathologic information in biomedical research.

Results

Inclusion criteria for scoring systems were a first description of a multiparametric, semiquantiative scoring systems which comprehensibly describe an approach to evaluate morphologic lesion. A comprehensive literature search using these criteria identified 153 originally desig

SUBMITTER: Klopfleisch R 

PROVIDER: S-EPMC3693904 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature