Genome-Wide Responses of Female Fruit Flies Subjected to Divergent Mating Regimes.

ABSTRACT: Elevated rates of mating and reproduction cause decreased female survival and lifetime reproductive success across a wide range of taxa from flies to humans. These costs are fundamentally important to the evolution of life histories. Here we investigate the potential mechanistic basis of this classic life history component. We conducted 4 independent replicated experiments in which female Drosophila melanogaster were subjected to 'high' and 'low' mating regimes, resulting in highly significant differences in lifespan. We sampled females for transcriptomic analysis at day 10 of life, before the visible onset of ageing, and used Tiling expression arrays to detect differential gene expression in two body parts (abdomen versus head+thorax). The divergent mating regimes were associated with sig

SUBMITTER: Gerrard DT 

PROVIDER: S-EPMC3694895 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature