RNAlyzer--novel approach for quality analysis of RNA structural models.

ABSTRACT: The continuously increasing amount of RNA sequence and experimentally determined 3D structure data drives the development of computational methods supporting exploration of these data. Contemporary functional analysis of RNA molecules, such as ribozymes or riboswitches, covers various issues, among which tertiary structure modeling becomes more and more important. A growing number of tools to model and predict RNA structure calls for an evaluation of these tools and the quality of outcomes their produce. Thus, the development of reliable methods designed to meet this need is relevant in the context of RNA tertiary structure analysis and can highly influence the quality and usefulness of RNA tertiary structure prediction in the nearest future. Here, we present RNAlyzer-a computational metho

SUBMITTER: Lukasiak P 

PROVIDER: S-EPMC3695499 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature