In silico platform for prediction of N-, O- and C-glycosites in eukaryotic protein sequences.

ABSTRACT: Glycosylation is one of the most abundant and an important post-translational modification of proteins. Glycosylated proteins (glycoproteins) are involved in various cellular biological functions like protein folding, cell-cell interactions, cell recognition and host-pathogen interactions. A large number of eukaryotic glycoproteins also have therapeutic and potential technology applications. Therefore, characterization and analysis of glycosites (glycosylated residues) in these proteins is of great interest to biologists. In order to cater these needs a number of in silico tools have been developed over the years, however, a need to get even better prediction tools remains. Therefore, in this study we have developed a new webserver GlycoEP for more accurate prediction of N-linked, O-linked

SUBMITTER: Chauhan JS 

PROVIDER: S-EPMC3695939 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature