Development of gold standard ion-selective electrode-based methods for fluoride analysis.

ABSTRACT:

Background/aims

Currently available techniques for fluoride analysis are not standardized. Therefore, this study was designed to develop standardized methods for analyzing fluoride in biological and nonbiological samples used for dental research.

Methods

A group of nine laboratories analyzed a set of standardized samples for fluoride concentration using their own methods. The group then reviewed existing analytical techniques for fluoride analysis, identified inconsistencies in the use of these techniques and conducted testing to resolve differences. Based on the results of the testing undertaken to define the best approaches for the analysis, the group developed recommendations for direct and microdiffusion methods using the fluoride ion-selective electrode.

Results

SUBMITTER: Martinez-Mier EA 

PROVIDER: S-EPMC3696354 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature