The association of ambient air pollution and traffic exposures with selected congenital anomalies in the San Joaquin Valley of California.

ABSTRACT: Congenital anomalies are a leading cause of infant mortality and are important contributors to subsequent morbidity. Studies suggest associations between environmental contaminants and some anomalies, although evidence is limited. We aimed to investigate whether ambient air pollutant and traffic exposures in early gestation contribute to the risk of selected congenital anomalies in the San Joaquin Valley of California, 1997-2006. Seven exposures and 5 outcomes were included for a total of 35 investigated associations. We observed increased odds of neural tube defects when comparing the highest with the lowest quartile of exposure for several pollutants after adjusting for maternal race/ethnicity, education, and multivitamin use. The adjusted odds ratio for neural tube defects among those w

SUBMITTER: Padula AM 

PROVIDER: S-EPMC3697063 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature