Risk of recurrent Helicobacter pylori infection 1 year after initial eradication therapy in 7 Latin American communities.

ABSTRACT:

Importance

The long-term effectiveness of Helicobacter pylori eradication programs for preventing gastric cancer will depend on recurrence risk and individual and community factors.

Objective

To estimate risk of H. pylori recurrence and assess factors associated with successful eradication 1 year after treatment.

Design, setting, and participants

Cohort analysis of 1463 randomized trial participants aged 21 to 65 years from 7 Latin American communities, who were treated for H. pylori and observed between September 2009 and July 2011.

Interventions

Randomization to 1 of 3 treatment groups: 14-day lansoprazole, amoxicillin, and clarithromycin (triple therapy); 5-day lansoprazole and amoxicillin followed by 5-day lansoprazole, clarithromycin, and metronidazole (se

SUBMITTER: Morgan DR 

PROVIDER: S-EPMC3697935 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature