Altered intra- and inter-regional synchronization of superior temporal cortex in deaf people.

ABSTRACT: Functional organization of the brain can be fundamentally altered by auditory deprivation. Previous studies found that the superior temporal cortex in deaf people is reorganized to process non-auditory stimuli, as revealed by the extrinsic task-induced brain activities. However, it is unknown how the intrinsic activities of this region are impacted by deafness. This study explored this issue using resting-state functional magnetic resonance imaging. We examined 60 congenitally deaf (CD) individuals, 39 acquired deaf (AD) individuals, and 38 hearing controls (HC), and focused on the effect of deafness on the intra- and inter-regional synchronization of different parts of superior temporal sulcus (STS). We found that intra-regional synchronization or regional homogeneity (ReHo) of the middle

SUBMITTER: Li Y 

PROVIDER: S-EPMC3698371 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature