Characterization of the upper respiratory tract microbiomes of patients with pandemic H1N1 influenza.

ABSTRACT: The upper respiratory tract microbiome has an important role in respiratory health. Influenza A is a common viral infection that challenges that health, and a well-recognized sequela is bacterial pneumonia. Given this connection, we sought to characterize the upper respiratory tract microbiota of individuals suffering from the pandemic H1N1 influenza A outbreak of 2009 and determine if microbiome profiles could be correlated with patient characteristics. We determined the microbial profiles of 65 samples from H1N1 patients by cpn60 universal target amplification and sequencing. Profiles were examined at the phylum and nearest neighbor "species" levels using the characteristics of patient gender, age, originating health authority, sample type and designation (STAT/non-STAT). At the phylum l

SUBMITTER: Chaban B 

PROVIDER: S-EPMC3699515 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature