Sodium thiosulfate therapy for calcific uremic arteriolopathy.

ABSTRACT:

Background and objective

Calcific uremic arteriolopathy (CUA) is an often fatal condition with no effective treatment. Multiple case reports and case series have described intravenous sodium thiosulfate (STS) administration in CUA, but no studies have systematically evaluated this treatment.

Design, setting, participants, & measurements

This study included 172 patients undergoing maintenance hemodialysis who had CUA and were treated with STS between August 2006 and June 2009 at Fresenius Medical Care North America. Of these, 85% completed STS therapy. Clinical, laboratory, and mortality data were abstracted from clinical information systems. Responses to survey questionnaires sent to treating physicians regarding patient-level outcomes were available for 53 patients. Effect

SUBMITTER: Nigwekar SU 

PROVIDER: S-EPMC3700696 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature