Randomized controlled trial of noninvasive positive pressure ventilation (NPPV) versus servoventilation in patients with CPAP-induced central sleep apnea (complex sleep apnea).

ABSTRACT:

Study objectives

To compare the treatment effect of noninvasive positive pressure ventilation (NPPV) and anticyclic servoventilation in patients with continuous positive airway pressure (CPAP)-induced central sleep apnea (complex sleep apnea).

Design

Randomized controlled trial.

Setting

Sleep center.

Patients

Thirty patients who developed complex sleep apnea syndrome (CompSAS) during CPAP treatment.

Interventions

NPPV or servoventilation.

Measurements and results

Patients were randomized to NPPV or servo-ventilation. Full polysomnography (PSG) was performed after 6 weeks. On CPAP prior to randomization, patients in the NPPV and servoventilator arm had comparable apnea-hypopnea indices (AHI, 28.6 ± 6.5 versus 27.7 ± 9.7 events/h (mean ± standard de

SUBMITTER: Dellweg D 

PROVIDER: S-EPMC3700713 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature