Extent and determinants of thermogenic responses to 24 hours of fasting, energy balance, and five different overfeeding diets in humans.

ABSTRACT:

Context

Individual variation in the ability to convert excess calories to heat and the effects of dietary macronutrient composition are unclear.

Objective

Stability and determinants of the energy expenditure (EE) response to overconsumption were assessed.

Design, setting, and participants

Twenty subjects (75% male) with normal glucose regulation were evaluated during 24 hours each of energy balance, fasting, and 5 different diets with 200% energy requirements in a clinical research unit.

Interventions

Five 1-day overfeeding diets were given in random order: high carbohydrate (75%) and low protein (3%); high carbohydrate and normal protein (20%); high fat (46%) and low protein; high fat (60%) and normal protein; and balanced (50% carbohydrates, 20% protein).

SUBMITTER: Thearle MS 

PROVIDER: S-EPMC3701281 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature