Synovial sarcoma presenting with huge mediastinal mass: a case report and review of literature.

ABSTRACT:

Background

Synovial sarcoma presenting in the mediastinum is exceedingly rare. Furthermore, data addressing optimal therapy is limited. Herein we present a case where an attempt to downsize the tumor to a resectable state with chemotherapy was employed.

Case presentation

A 32 year female presented with massive pericardial effusion and unresectable huge mediastinal mass. Computed axial tomography scan - guided biopsy with adjunctive immunostains and molecular studies confirmed a diagnosis of synovial sarcoma. Following three cycles of combination Ifosfamide and doxorubicin chemotherapy, no response was demonstrated. The patient refused further therapy and had progression of her disease 4 months following the last cycle.

Conclusion

Synovial sarcoma presenting with unres

SUBMITTER: Salah S 

PROVIDER: S-EPMC3701506 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature