Associations of SAA1 gene polymorphism with lipid lelvels and osteoporosis in Chinese women.

ABSTRACT:

Background

The development of osteoporosis is associated with several risk factors, such as genetic polymorphisms and enviromental factors. This study assessed the correlation between SAA1 gene rs12218 polymorphism and HDL-C lelvels and osteoporosis in a population of Chinese women.

Methods

A total of 387 postmenopausal female patients who were diagnosed with osteoporosis (case group) based on bone mineral density measurements via dual-energy x-ray absorptiometry and 307 females with no osteoporosis (control group) were included in this study. Correlations between SAA1 gene rs12218 polymorphism and osteoporosis and HDL-C level were investigated through the identification of SAA1 gene rs12218 polymorphism genotypes using the polymerase chain reaction-restriction fragment leng

SUBMITTER: Feng ZP 

PROVIDER: S-EPMC3702468 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature