Genomic clustering and co-regulation of transcriptional networks in the pathogenic fungus Fusarium graminearum.

ABSTRACT:

Background

Genes for the production of a broad range of fungal secondary metabolites are frequently colinear. The prevalence of such gene clusters was systematically examined across the genome of the cereal pathogen Fusarium graminearum. The topological structure of transcriptional networks was also examined to investigate control mechanisms for mycotoxin biosynthesis and other processes.

Results

The genes associated with transcriptional processes were identified, and the genomic location of transcription-associated proteins (TAPs) analyzed in conjunction with the locations of genes exhibiting similar expression patterns. Highly conserved TAPs reside in regions of chromosomes with very low or no recombination, contrasting with putative regulator genes. Co-expression group pr

SUBMITTER: Lawler K 

PROVIDER: S-EPMC3703260 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature