Gender differences of airway dimensions in anatomically matched sites on CT in smokers.

ABSTRACT:

Rationale and objectives

There are limited data on, and controversies regarding gender differences in the airway dimensions of smokers. Multi-detector CT (MDCT) images were analyzed to examine whether gender could explain differences in airway dimensions of anatomically matched airways in smokers.

Materials and methods

We used VIDA imaging software to analyze MDCT scans from 2047 smokers (M:F, 1021:1026) from the COPDGene® cohort. The airway dimensions were analyzed from segmental to subsubsegmental bronchi. We compared the differences of luminal area, inner diameter, wall thickness, wall area percentage (WA%) for each airway between men and women, and multiple linear regression including covariates (age, gender, body sizes, and other relevant confounding factors) was used t

SUBMITTER: Kim YI 

PROVIDER: S-EPMC3703311 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature