Antituberculosis cycloartane triterpenoids from Radermachera boniana.

ABSTRACT: Three new triterpenoids, bonianic acids A (1) and B (2) and 3-O-acetyluncaric acid (3), were isolated from the leaves and twigs of Radermachera boniana, together with six known compounds, ursolic acid (4), oleanolic acid (5), 3-epi-oleanolic acid (6), 3α-O-acetyl-α-boswellic acid (7), ergosterol peroxide (8), and β-sitostenone (9). Ergosterol peroxide (8) and bonianic acids A (1) and B (2) exhibited significant activity against Mycobacterium tuberculosis H37Rv strain.

SUBMITTER: Truong NB 

PROVIDER: S-EPMC3703769 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature