Molecular population genetics of inversion breakpoint regions in Drosophila pseudoobscura.

ABSTRACT: Paracentric inversions in populations can have a profound effect on the pattern and organization of nucleotide variability along a chromosome. Regions near inversion breakpoints are expected to have greater levels of differentiation because of reduced genetic exchange between different gene arrangements whereas central regions in the inverted segments are predicted to have lower levels of nucleotide differentiation due to greater levels of genetic flux among different karyotypes. We used the inversion polymorphism on the third chromosome of Drosophila pseudoobscura to test these predictions with an analysis of nucleotide diversity of 18 genetic markers near and away from inversion breakpoints. We tested hypotheses about how the presence of different chromosomal arrangements affects the pat

SUBMITTER: Wallace AG 

PROVIDER: S-EPMC3704243 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature