Chemoecological screening reveals high bioactivity in diverse culturable Portuguese marine cyanobacteria.

ABSTRACT: Marine cyanobacteria, notably those from tropical regions, are a rich source of bioactive secondary metabolites. Tropical marine cyanobacteria often grow to high densities in the environment, allowing direct isolation of many secondary metabolites from field-collected material. However, in temperate environments culturing is usually required to produce enough biomass for investigations of their chemical constituents. In this work, we cultured a selection of novel and diverse cyanobacteria isolated from the Portuguese coast, and tested their organic extracts in a series of ecologically-relevant bioassays. The majority of the extracts showed activity in at least one of the bioassays, all of which were run in very small scale. Phylogenetically related isolates exhibited different activity pro

SUBMITTER: Leao PN 

PROVIDER: S-EPMC3705407 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature