Genome sequence and comparative analysis of Avibacterium paragallinarum.

ABSTRACT:

Background

Avibacterium paragallinarum, the causative agent of infectious coryza, is a highly contagious respiratory acute disease of poultry, which affects commercial chickens, laying hens and broilers worldwide.

Methodology

In this study, we performed the whole genome sequencing, assembly and annotation of a Peruvian isolate of A. paragallinarum. Genome was sequenced in a 454 GS FLX Titanium system. De novo assembly was performed and annotation was completed with GS De Novo Assembler 2.6 using the H. influenzae str. F3031 gene model. Manual curation of the genome was performed with Artemis. Putative function of genes was predicted with Blast2GO. Virulence factors were identified by comparison with the Virulence Factor Database.

Results

The genome obtained has a leng

SUBMITTER: Requena D 

PROVIDER: S-EPMC3705629 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature