Elastomeric microparticles for acoustic mediated bioseparations.

ABSTRACT:

Background

Acoustophoresis has been utilized successfully in applications including cell trapping, focusing, and purification. One current limitation of acoustophoresis for cell sorting is the reliance on the inherent physical properties of cells (e.g., compressibility, density) instead of selecting cells based upon biologically relevant surface-presenting antigens. Introducing an acoustophoretic cell sorting approach that allows biochemical specificity may overcome this limitation, thus advancing the value of acoustophoresis approaches for both the basic research and clinical fields.

Results

The results presented herein demonstrate the ability for negative acoustic contrast particles (NACPs) to specifically capture and transport positive acoustic contrast particles (PACPs)

SUBMITTER: Johnson LM 

PROVIDER: S-EPMC3706277 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature