Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes.

ABSTRACT:

Background

The phylum Platyhelminthes (flatworms) contains an important group of bilaterian organisms responsible for many debilitating and chronic infectious diseases of human and animal populations inhabiting the planet today. In addition to their biomedical and veterinary relevance, some platyhelminths are also frequently used models for understanding tissue regeneration and stem cell biology. Therefore, the molecular (genetic and epigenetic) characteristics that underlie trophic specialism, pathogenicity or developmental maturation are likely to be pivotal in our continued studies of this important metazoan group. Indeed, in contrast to earlier studies that failed to detect evidence of cytosine or adenine methylation in parasitic flatworm taxa, our laboratory has recently defin

SUBMITTER: Geyer KK 

PROVIDER: S-EPMC3710501 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature