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Clinical associations of the metabolic syndrome in systemic lupus erythematosus: data from an international inception cohort.


ABSTRACT:

Background

The metabolic syndrome (MetS) may contribute to increased cardiovascular risk in systemic lupus erythematosus (SLE). We aimed to examine the association of demographic factors, lupus phenotype and therapy exposure with the presence of MetS.

Methods

The Systemic Lupus International Collaborating Clinics Registry for Atherosclerosis inception cohort enrolled recently diagnosed (<15 months) SLE patients from 30 centres across 11 countries from 2000. Clinical, laboratory and therapeutic data were collected according to a standardised protocol. MetS was defined according to the 2009 consensus statement from the International Diabetes Federation. Univariate and backward stepwise multivariate logistic regression were used to assess the relationship of individual variable

SUBMITTER: Parker B 

PROVIDER: S-EPMC3711497 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature