Yeast "make-accumulate-consume" life strategy evolved as a multi-step process that predates the whole genome duplication.

ABSTRACT: When fruits ripen, microbial communities start a fierce competition for the freely available fruit sugars. Three yeast lineages, including baker's yeast Saccharomyces cerevisiae, have independently developed the metabolic activity to convert simple sugars into ethanol even under fully aerobic conditions. This fermentation capacity, named Crabtree effect, reduces the cell-biomass production but provides in nature a tool to out-compete other microorganisms. Here, we analyzed over forty Saccharomycetaceae yeasts, covering over 200 million years of the evolutionary history, for their carbon metabolism. The experiments were done under strictly controlled and uniform conditions, which has not been done before. We show that the origin of Crabtree effect in Saccharomycetaceae predates the whole ge

SUBMITTER: Hagman A 

PROVIDER: S-EPMC3711898 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature