Triplex-Inspector: an analysis tool for triplex-mediated targeting of genomic loci.

ABSTRACT:

Summary

At the heart of many modern biotechnological and therapeutic applications lies the need to target specific genomic loci with pinpoint accuracy. Although landmark experiments demonstrate technological maturity in manufacturing and delivering genetic material, the genomic sequence analysis to find suitable targets lags behind. We provide a computational aid for the sophisticated design of sequence-specific ligands and selection of appropriate targets, taking gene location and genomic architecture into account.

Availability

Source code and binaries are downloadable from www.bioinformatics.org.au/triplexator/inspector.

Contact

[e-mail]

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Buske FA 

PROVIDER: S-EPMC3712220 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature