Neuroeconomics and adolescent substance abuse: individual differences in neural networks and delay discounting.

ABSTRACT:

Objective

Many adolescents with substance use problems show poor response to evidence-based treatments. Treatment outcome has been associated with individual differences in impulsive decision making as reflected by delay discounting (DD) rates (preference for immediate rewards). Adolescents with higher rates of DD were expected to show greater neural activation in brain regions mediating impulsive/habitual behavioral choices and less activation in regions mediating reflective/executive behavioral choices.

Method

Thirty adolescents being treated for substance abuse completed a DD task optimized to balance choices of immediate versus delayed rewards, and a control condition accounted for activation during magnitude valuation. A group independent component analysis on functiona

SUBMITTER: Stanger C 

PROVIDER: S-EPMC3712894 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature