Chronic kidney disease associated with perinatal HIV infection in children and adolescents.

ABSTRACT:

Background

This study describes the incidence, clinical and demographic characteristics, and spectrum of chronic kidney disease (CKD) in youths with perinatal HIV-1 infection.

Methods

Retrospective analysis between May 1993 and December 2006 of subjects with renal disease followed in the Pediatric AIDS Clinical Trials Group 219/219C multicenter study examining the long-term consequences of perinatal HIV infection. Diagnosis confirmation was made utilizing a questionnaire mailed to research sites. Participants with CKD of other etiology than HIV were excluded. Outcome measures were biopsy-diagnosed CKD and, in the absence of biopsy, HIV-associated nephropathy (HIVAN) using established clinical criteria.

Results

Questionnaires on 191 out of 2,102 participants identified

SUBMITTER: Purswani MU 

PROVIDER: S-EPMC3715373 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature