Evolutionary dynamics of copy number variation in pig genomes in the context of adaptation and domestication.

ABSTRACT:

Background

Copy number variable regions (CNVRs) can result in drastic phenotypic differences and may therefore be subject to selection during domestication. Studying copy number variation in relation to domestication is highly relevant in pigs because of their very rich natural and domestication history that resulted in many different phenotypes. To investigate the evolutionary dynamic of CNVRs, we applied read depth method on next generation sequence data from 16 individuals, comprising wild boars and domestic pigs from Europe and Asia.

Results

We identified 3,118 CNVRs with an average size of 13 kilobases comprising a total of 39.2 megabases of the pig genome and 545 overlapping genes. Functional analyses revealed that CNVRs are enriched with genes related to sensory perce

SUBMITTER: Paudel Y 

PROVIDER: S-EPMC3716681 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature