Proteogenomic analysis of a thermophilic bacterial consortium adapted to deconstruct switchgrass.

ABSTRACT: Thermophilic bacteria are a potential source of enzymes for the deconstruction of lignocellulosic biomass. However, the complement of proteins used to deconstruct biomass and the specific roles of different microbial groups in thermophilic biomass deconstruction are not well-explored. Here we report on the metagenomic and proteogenomic analyses of a compost-derived bacterial consortium adapted to switchgrass at elevated temperature with high levels of glycoside hydrolase activities. Near-complete genomes were reconstructed for the most abundant populations, which included composite genomes for populations closely related to sequenced strains of Thermus thermophilus and Rhodothermus marinus, and for novel populations that are related to thermophilic Paenibacilli and an uncultivated subdivis

SUBMITTER: D'haeseleer P 

PROVIDER: S-EPMC3716776 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature