Structure, function, and behaviour of computational models in systems biology.

ABSTRACT:

Background

Systems Biology develops computational models in order to understand biological phenomena. The increasing number and complexity of such "bio-models" necessitate computer support for the overall modelling task. Computer-aided modelling has to be based on a formal semantic description of bio-models. But, even if computational bio-models themselves are represented precisely in terms of mathematical expressions their full meaning is not yet formally specified and only described in natural language.

Results

We present a conceptual framework - the meaning facets - which can be used to rigorously specify the semantics of bio-models. A bio-model has a dual interpretation: On the one hand it is a mathematical expression which can be used in computational simulations (intri

SUBMITTER: Knupfer C 

PROVIDER: S-EPMC3716781 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature