The McNemar test for binary matched-pairs data: mid-p and asymptotic are better than exact conditional.

ABSTRACT:

Background

Statistical methods that use the mid-p approach are useful tools to analyze categorical data, particularly for small and moderate sample sizes. Mid-p tests strike a balance between overly conservative exact methods and asymptotic methods that frequently violate the nominal level. Here, we examine a mid-p version of the McNemar exact conditional test for the analysis of paired binomial proportions.

Methods

We compare the type I error rates and power of the mid-p test with those of the asymptotic McNemar test (with and without continuity correction), the McNemar exact conditional test, and an exact unconditional test using complete enumeration. We show how the mid-p test can be calculated using eight standard software packages, including Excel.

Results

The mi

SUBMITTER: Fagerland MW 

PROVIDER: S-EPMC3716987 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature