Simplified programming and control of automated radiosynthesizers through unit operations.

ABSTRACT:

Background

Many automated radiosynthesizers for producing positron emission tomography (PET) probes provide a means for the operator to create custom synthesis programs. The programming interfaces are typically designed with the engineer rather than the radiochemist in mind, requiring lengthy programs to be created from sequences of low-level, non-intuitive hardware operations. In some cases, the user is even responsible for adding steps to update the graphical representation of the system. In light of these unnecessarily complex approaches, we have created software to perform radiochemistry on the ELIXYS radiosynthesizer with the goal of being intuitive and easy to use.

Methods

Radiochemists were consulted, and a wide range of radiosyntheses were analyzed to determine a com

SUBMITTER: Claggett SB 

PROVIDER: S-EPMC3717018 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature