Diastolic dysfunction is associated with an increased risk of contrast-induced nephropathy: a retrospective cohort study.

ABSTRACT:

Background

Contrast-induced nephropathy (CIN) is the third leading cause of hospital-acquired acute kidney injury, and it is associated with poor long-term clinical outcomes. Although systolic heart failure is a well-known risk factor for CIN, no studies have yet evaluated the association between diastolic dysfunction and CIN.

Methods

We conducted a retrospective study of 735 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) and had an echocardiography performed within one month of the procedure at our institute, between January 2009 and December 2010. CIN was defined as an increase of ≥ 0.5 mg/dL or ≥ 25% in serum creatinine level during the 72 hours following PTCA.

Results

CIN occurred in 64 patients (8.7%). Patients with CIN were older, h

SUBMITTER: Koo HM 

PROVIDER: S-EPMC3717078 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature