Comparison of indocyanine green angiography and laser speckle contrast imaging for the assessment of vasculature perfusion.

ABSTRACT:

Background

Assessment of the vasculature is critical for overall success in cranial vascular neurological surgery procedures. Although several methods of monitoring cortical perfusion intraoperatively are available, not all are appropriate or convenient in a surgical environment. Recently, 2 optical methods of care have emerged that are able to obtain high spatial resolution images with easily implemented instrumentation: indocyanine green (ICG) angiography and laser speckle contrast imaging (LSCI).

Objective

To evaluate the usefulness of ICG and LSCI in measuring vessel perfusion.

Methods

An experimental setup was developed that simultaneously collects measurements of ICG fluorescence and LSCI in a rodent model. A 785-nm laser diode was used for both excitation of th

SUBMITTER: Towle EL 

PROVIDER: S-EPMC3718844 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature