Plant F-box protein evolution is determined by lineage-specific timing of major gene family expansion waves.

ABSTRACT: F-box proteins (FBPs) represent one of the largest and fastest evolving gene/protein families in the plant kingdom. The FBP superfamily can be divided in several subfamilies characterized by different C-terminal protein-protein interaction domains that recruit targets for proteasomal degradation. Hence, a clear picture of their phylogeny and molecular evolution is of special interest for the general understanding of evolutionary histories of multi-domain and/or large protein families in plants. In an effort to further understand the molecular evolution of F-box family proteins, we asked whether the largest subfamily in Arabidopsis thaliana, which carries a C-terminal F-box associated domain (FBA proteins) shares evolutionary patterns and signatures of selection with other FBPs. To address

SUBMITTER: Navarro-Quezada A 

PROVIDER: S-EPMC3719486 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature