Involvement of the novel two-component NsrRS and LcrRS systems in distinct resistance pathways against nisin A and nukacin ISK-1 in Streptococcus mutans.

ABSTRACT: The novel two-component systems NsrRS and LcrRS are individually associated with resistance against the distinct lantibiotics nisin A and nukacin ISK-1 in Streptococcus mutans. NsrRS regulates the expression of NsrX, which is associated with nisin A binding, and LcrRS regulates the expression of the ABC transporter LctFEG.

SUBMITTER: Kawada-Matsuo M 

PROVIDER: S-EPMC3719517 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature