Molecular identification and susceptibility pattern of clinical Nocardia species: Emergence of Nocardia crassostreae as an agent of invasive nocardiosis.

ABSTRACT:

Background

Nocardia species are rare, opportunistic organisms that cause disease in both immunocompetent and immunocompromised individuals.

Objective

To investigate the clinical presentations of various Nocardia infections based on the 16S ribosomal RNA gene of the isolate, as well as related risk factors and susceptibility patterns to antimicrobial agents.

Methods

Thirteen patients with a diagnosis of nocardiosis were included in the present study. Seven Nocardia species were identified by 16S ribosomal RNA. Susceptibility testing was performed using six antimicrobial agents.

Results

Five patients were immunocompromised, and eight were immunocompetent with predisposing factors including cystic fibrosis, tuberculosis and ophthalmic infections. Nocardia caused p

SUBMITTER: Taj-Aldeen SJ 

PROVIDER: S-EPMC3720011 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature