Pediatric ptosis as a sign of treatable autonomic dysfunction.

ABSTRACT:

Purpose

To report the ophthalmic findings in young patients with dopamine β-hydroxylase deficiency and to assess them in the context of other reports in an attempt to discern if ophthalmic criteria may assist in early detection of this debilitating, yet treatable, disorder.

Design

Prospective, observational case series.

Methods

An ophthalmic examination, including measuring intraocular and systemic blood pressures while supine, sitting, and standing, and eyelid function and pupillary function testing, was completed on 3 young patients with recently documented dopamine β-hydroxylase deficiency at a single institution.

Results

Mean arterial blood pressures were 90.1 ± 18.5 mm Hg supine, 79.1 ± 25.7 mm Hg sitting, and 45.8 ± 11.6 mm Hg standing (P = .021). Mean in

SUBMITTER: Phillips L 

PROVIDER: S-EPMC3720787 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature