Advanced fibrosis in nonalcoholic fatty liver disease: noninvasive assessment with MR elastography.

ABSTRACT:

Purpose

To evaluate the diagnostic accuracy of magnetic resonance (MR) elastography as a method to help diagnose clinically substantial fibrosis in patients with nonalcoholic fatty liver disease (NAFLD) and, by using MR elastography as a reference standard, to compare various laboratory marker panels in the identification of patients with NAFLD and advanced fibrosis.

Materials and methods

This retrospective study was institutional review board approved and HIPAA complaint. Informed consent was waived. This study was conducted in patients with NAFLD, who were identified by imaging characteristics consistent with steatosis in a prospective database that tracks all MR elastographic examinations. Six laboratory-based models of fibrosis were compared with MR elastographic results

SUBMITTER: Kim D 

PROVIDER: S-EPMC3721049 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature