Phylogeography and spatio-temporal genetic variation of Aedes aegypti (Diptera: Culicidae) populations in the Florida Keys.

ABSTRACT: Aedes aegypti (L.) is the principal mosquito vector of dengue fever, the second-most deadly vector-borne disease in the world. In Ae. aegypti and other arthropod disease vectors, genetic markers can be used to inform us about processes relevant to disease spread, such as movement of the vectors across space and the temporal stability of vector populations. In late 2009, 27 locally acquired cases of dengue fever were reported in Key West, FL. The last dengue outbreak in the region occurred in 1934. In this study, we used 12 microsatellite loci to examine the genetic structure of 10 Ae. aegypti populations from throughout the Florida Keys and Miami to assess gene flow along the region's main roadway, the Overseas Highway. We also assessed temporal genetic stability of populations in Key West

SUBMITTER: Brown JE 

PROVIDER: S-EPMC3721520 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature